Ox40/trail fusion proteins

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 19/00 (2006.01) A61K 38/17 (2006.01) A61P 35/00 (2006.01) A61P 37/06 (2006.01) C07K 14/525 (2006.01) C07K 14/715 (2006.01)

Patent

CA 2755198

Fusion proteins which act on the OX40/TRAIL signaling axes are provided. The proteins are useful in the treatment or amelioration of autoimmune diseases, particularly multiple sclerosis, and alloimmune diseases, as well as cancer.

L'invention porte sur des protéines de fusion qui agissent sur les axes de signalisation OX40/TRAIL. Les protéines sont utiles dans le traitement ou l'amélioration de maladies auto-immunes, en particulier de la sclérose en plaques, et de maladies allo-immunes, ainsi que du cancer.

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