Oxa- and thiazole derivatives useful as antidiabetic and...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 413/12 (2006.01) A61K 31/421 (2006.01) A61K 31/426 (2006.01) A61K 31/4439 (2006.01) A61P 3/06 (2006.01) A61P 3/10 (2006.01) C07D 263/32 (2006.01) C07D 263/58 (2006.01) C07D 277/24 (2006.01) C07D 413/14 (2006.01) C07D 417/04 (2006.01) C07D 417/12 (2006.01) C07D 495/04 (2006.01) C07D 521/00 (2006.01)

Patent

CA 2388452

Compounds are provided which have structure (I), wherein Q is C or N; A is O or S; Z is O or a bond; X is CH or N and R1, R2, R2a, R2b, R2c, R3, y x, m, and n are as defined herein, which compounds are useful as antidiabetic, hypolipidemic, and antiobesity agents.

L'invention concerne des composés ayant la structure (I), dans laquelle Q représente C ou N, A représente O ou S, Z représente O ou une liaison, X représente CH ou N et R<1>, R<2>, R<2a>, R<2b>, R<2c>, R<3>, Y, x, m et n sont tels que définis dans la description. Ces composés sont utiles en tant qu'antidiabétiques, hypolipidémiants et agents contre l'obésité.

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