Oxa diacids and related compounds for treating skin conditions

A - Human Necessities – 61 – K

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A61K 8/63 (2006.01) C07C 59/305 (2006.01) C07C 69/708 (2006.01)

Patent

CA 2251746

Described are the use of compounds of formula (1), as active principals for treating skin conditions; compositions containing these compounds; and methods of treating skin conditions using these compounds and compositions, wherein R4 is (CR5R6-CR7R8-X1)n-CR9R10- C(=X2)X3R11, n is an integer from 1 to 18; R1, R2, R3, R5, R6, R7, R8, R9, R10 and R11, are independently, hydrogen or non-hydrogen substituents; and X, X1, X2, X3, Y and Z are independently O, NH or S.

Description de l'utilisation de composés de formule (1), comme principes actifs pour traiter les affections cutanées; compositions renfermant ces composés; méthodes pour traiter les affections cutanées à l'aide de ces composés et compositions, où : R4 est (CR5R6-CR7R8-X1)n-CR9R10- C(=X2)X3R11, n étant un entier de 1 à 18; R1, R2, R3, R5, R6, R7, R8, R9, R10 et R11 sont indépendamment de l'hydrogène ou d'autres substituants; enfin X, X1, X2, X3, Y et Z sont indépendamment O, NH ou S.

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