C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/299, 260/360
C07D 311/94 (2006.01) C07D 405/04 (2006.01) C07D 405/12 (2006.01) C07D 409/04 (2006.01) C07D 413/12 (2006.01) C07D 487/04 (2006.01)
Patent
CA 1300138
ABSTRACT The invention relates to novel oxabicycloheptane derivatives of the formula: Image where D is a hydrogen or halogen atom, or a hydroxyl, alkoxy, arylalkoxy, acyloxy, dialkylcarbamoyloxy or amidoalkyloxy group; B is a substituted or unsubsti- tuted phenyl, thienyl or furyl group; /A\ is the group Image (where ? is 0 or 1; m and n are each 1 or more, pro- vided that m + n is an integer of 2 - 8; R1 is an alkylamino, dialkylamino, arylalkylamino, morpholino, thiomorpholino, 1-pyrrolidinyl, piperidino, N-alkyl- piperazinyl, N-hydroxyalkylpiperazinyl or pyrrolizi- dinyl group; and R2 is a lower alkyl or hydroxyl group), or the group Image (where ?, m, n, R1 and R2 have the aforesaid meanings), or the group Image (where R3 and R4 which may be the same or different each represents a hydrogen atom or a lower alkyl, alkoxy-carbonyl or acyl group), or the group Image (where m, ?, n, R1 and R2 have the aforesaid meanings). The oxabicycloheptane derivatives of the invention are effective in ameliorating or eliminating the symptoms that appear either as a result of organic disorders in the brain or on account of pathergasia. These com- pounds also have antidepressant effects and are useful as psychopharmaceuticals.
530795
Imao Kayoko
Miyano Seiji
Satoh Fumio
Sumoto Kunihiro
Suzuki Kenji
Suntory Limited
Swabey Ogilvy Renault
LandOfFree
Oxabicycloheptane derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Oxabicycloheptane derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Oxabicycloheptane derivatives will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1296111