Oxadiazole-alkyl-purine derivatives

Details Oxadiazole-alkyl-purine derivatives Oxadiazole-alkyl-purine derivatives

C - Chemistry, Metallurgy

07

D

167/220, 260/242

C07D 473/06 (2006.01) A61K 31/52 (2006.01)

Patent

CA 1288432

A B S T R A C T The invention relates to new oxadiazole-alkyl-purine- derivatives of the general Formula I Image and pharmaceutically acceptable salts thereof (wherein A stands for C1-4 alkylene and R1 represents C1-6 alkyl, hydroxyalkyl, halogenoalkyl, carboxyalkyl, C5-6 cycloalkyl or aminoalkyl of the general Formula -(CH2)n-NR2R3 in which group n is an integral 1-3; R2 and R3 each stand for hydrogen or C1-4 alkyl or together with the adjacent nitrogen atom they are attached to form a 5- or 6-membered nitrogen containing heterocyclic ring which may optionally comprise a further nitrogen atom or an oxygen atom as heteroatom; or R1 stands for phenyl, hydroxyphenyl, carboxyphenyl, benzyl or dimethoxybenzyl The compounds of the general Formula I can be prepared by methods known per se and can be used in therapy as antitussive agents.

548853

Affiliated with

Also associated with

Rating

Oxadiazole-alkyl-purine derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Oxadiazole-alkyl-purine derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Oxadiazole-alkyl-purine derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1187068