Oxadiazole derivatives active on sphingosine-1-phosphate (s1p)

Details Oxadiazole derivatives active on sphingosine-1-phosphate (s1p) Oxadiazole derivatives active on sphingosine-1-phosphate (s1p)

C - Chemistry, Metallurgy

07

D

C07D 413/04 (2006.01) A61K 31/4725 (2006.01) A61P 17/00 (2006.01) A61P 37/00 (2006.01) C07D 217/06 (2006.01) C07D 217/16 (2006.01) C07D 217/22 (2006.01) C07D 413/14 (2006.01)

Patent

CA 2710067

The present application discloses oxadiazote based compounds of Formula (I) active on sphingosine-1-phosphate (S1P) in particular useful to treat lupus erythematosus. A is phenyl or a 5 or 6-membered heleroaryl ring; B is selected from one of the following; Formulae: (a) (b) (c)

La présente invention décrit des composés à base d'oxadiazole de formule (I) actifs sur la sphingosine-1-phosphate (S1P), en particulier utiles pour traiter le lupus érythémateux. A est un groupe phényle ou un cycle hétéroaryle à 5 ou 6 chaînons; B est choisi parmi : Formules : (a) (b) (c)

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