Oxadiazolyl imidabenzodiazepine derivatives, a method of...

Details Oxadiazolyl imidabenzodiazepine derivatives, a method of... Oxadiazolyl imidabenzodiazepine derivatives, a method of...

C - Chemistry, Metallurgy

07

D

260/239.4

C07D 471/14 (2006.01) C07D 271/06 (2006.01) C07D 487/04 (2006.01) C07D 487/14 (2006.01)

Patent

CA 1261322

Abstract of the Disclosure New oxadiazolyl imidazobenzodiazepine derivatives having the formula Image wherein R3 has the formula Image Image or wherein R '' is hydrogen, ?-6 alkyl C1-6 alkoxymethyl or C3-6 - cycloalkyl; R4 is hydrogen; R5 is C1-6 alkyl or R4 and R5 together form a 2-4 membered alkylene bridge; and RA is C1-6 alkyl, C1-6 alkoxy, or C1-3 trifluoroalkyl, pharmaceutical composi- tions thereof, and method of treating therewith, are disclosed. The compounds and pharmaceutical compositions are useful in the amelioration, mitigation, or elimination of central nervous system disorders related to benzodiazepine receptors and especially as anticonvulsants, anxiolytics, hypnotics, and nootropics.

503329

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