C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 413/12 (2006.01) A61K 31/4245 (2006.01) A61P 31/14 (2006.01)
Patent
CA 2459376
Oxadiazolyl-phenoxyalkylisoxazoles and pharmaceutically acceptable salts thereof, compositions comprising oxadiazolyl-phenoxyalkylisoxazole compounds or pharmaceutically acceptable salts thereof and methods for using oxadiazolyl- phenoxyalkylisoxazole compounds or pharmaceutically acceptable salts thereof as anti-picornaviral agents are described herein. The methods include using pleconaril as a prodrug for conversion to anti-picornaviral compounds in vivo.
L'invention concerne des oxadiazolyl-phenoxyalkylisoxazoles, leurs sels pharmaceutiquement acceptables, des compositions contenant des oxadiazolyl-phenoxyalkylisoxazoles ou leurs sels pharmaceutiquement acceptables, et des procédés d'utilisation d'oxadiazolyl-phenoxyalkylisoxazoles ou de leurs sels pharmaceutiquement acceptables comme agents anti-picornavirus. Lesdits procédés consistent à utiliser du pleconaril comme promédicament pour la conversion <i>in vivo</i> en composés anti-picornavirus.
Nitz Theodore J.
Rhodes Gerald
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Viropharma Incorporated
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