Oxazinoindole-and thiazinoindole derivatives

C - Chemistry – Metallurgy – 07 – D

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260/244.7

C07D 498/04 (2006.01) C07D 209/08 (2006.01)

Patent

CA 1036596

ABSTRACT Oxazinoindole derivatives characterized by having an amino(lower)alkyl radical attached to the 1 position of an 1H-1,4-oxazino[4,3-a]indole nucleus are disclosed. The amino portion of the amino(lower)alkyl radical may be further substituted with one or two lower alkyl groups or incorporated in a heterocyclic amine radical. The derivatives are substituted further at positions 1 and 10 and may be optionally substituted at positions 3, 4, 6, 7, 8 and 9. The oxazinoindole derivatives of this invention are useful antidepressant and antiulcer agents. Methods for the preparation and use of these derivatives are also disclosed.

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