Oxazolidin-2-one derivatives as hypoglycemic agents

Details Oxazolidin-2-one derivatives as hypoglycemic agents Oxazolidin-2-one derivatives as hypoglycemic agents

C - Chemistry, Metallurgy

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C07D 263/24 (2006.01) C07D 263/20 (2006.01) C07D 263/48 (2006.01) C07D 413/04 (2006.01) C07D 413/10 (2006.01) C07D 417/10 (2006.01)

Patent

CA 1305152

OXAZOLIDIN-2-ONE DERIVATIVES AS HYPOGLYCEMIC AGENTS ABSTRACT Certain 4-[2-(5-(optionally-substituted-aryl- and heteroaryl)oxazolidin-2-on-3-yl)alkyl]benæoic acids and ester, glycinamide, oxazole and thiazolidinedione derivatives thereof of the formula: Image (I) wherein Rb is Image or Image W is sulfur or oxygen; X and X1 are each independently H, C1, F or CF3; Y is -COORl, Image Image or Image Ra, R1, R2 and R3 are each independently H or CH3; and R4 is CH3 or CF3; are useful as hypoglycemic agents.

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