Oxazolidinones containing oxindoles as antibacterial agents

Details Oxazolidinones containing oxindoles as antibacterial agents Oxazolidinones containing oxindoles as antibacterial agents

C - Chemistry, Metallurgy

07

D

C07D 413/04 (2006.01) A61K 31/422 (2006.01) A61P 31/04 (2006.01)

Patent

CA 2576041

The present invention relates to novel oxazolidinones derivatives of oxindoles of formula I, or a pharmaceutically acceptable salt thereof wherein Y1 is CH- or-CF-; R1is -C1-4alkyl, optionally substituted with a fluoro atom, or R1 is - C3-5cycloalkyl; and R2 is -H or -CH3. These compounds are useful as antibacterial agents.

La présente invention concerne de nouveaux dérivés oxazolidinones d'oxindoles de formule I, ou un sel pharmaceutiquement acceptable de ceux-ci où Y1 est CH- ou CF- ; R1 est un alkyle en C1-4, facultativement substitué par un atome de fluor, ou R1 est un cycloalkyle en C3-5 ; et R2 est -H ou -CH3. Ces composés sont utiles en tant qu'agents antibactériens.

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