A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/5377 (2006.01) A61P 1/00 (2006.01) A61P 9/10 (2006.01)
Patent
CA 2729687
The present invention relates to the use of selective inhibitors of coagulation factor Xa, in particular of oxazolidinones of the formula (I), for the treatment and/or prophylaxis of inflammatory conditions of the gastrointestinal tract such as inflammatory bowel disease (IBD) and celiac disease and/or disorders related to inflammatory bowel disease (IBD) and/or celiac disease such as thromboembolic events (including e.g. pulmonary embolism (PE), arterial and venous thrombosis, myocardial infarction, stroke) as well as their use for the preparation of pharmaceutical drugs for the treatment and/or prophylaxis of inflammatory bowel disease (IBD) and/or celiac disease and/or disorders related to inflammatory bowel disease (IBD) and/or celiac disease such as thromboembolic events.
La présente invention porte sur l'utilisation d'inhibiteurs sélectifs du facteur de coagulation Xa, en particulier d'oxazolidinones de formule (I), pour le traitement et/ou la prévention des affections inflammatoires du tractus gastro-intestinal telles qu'une infection abdominale inflammatoire (IBD) et une maladie cliaque et/ou des troubles apparentés à une infection abdominale inflammatoire (IBD) et/ou une maladie cliaque, telle que des événements thromboemboliques (incluant par exemple une embolie pulmonaire (PE), une thrombose artérielle et veineuse, un infarctus du myocarde, un accident vasculaire cérébral), ainsi que sur leur utilisation pour la préparation de médicaments pharmaceutiques pour le traitement et/ou la prévention d'une affection abdominale inflammatoire (IBD) et/ou d'une maladie cliaque et/ou de troubles liés à une affection abdominale inflammatoire (IBD) et/ou une maladie cliaque, telle que des événements thromboemboliques.
Mcdonald Fiona
Perzborn Elisabeth
Roehrig Susanne
Thielemann Wolfgang
von Degenfeld Georges
Bayer Schering Pharma Aktiengesellschaft
Fetherstonhaugh & Co.
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