Oxazolidone derivative

Details Oxazolidone derivative Oxazolidone derivative

C - Chemistry, Metallurgy

07

D

C07D 417/04 (2006.01) A61K 31/41 (2006.01) A61K 31/445 (2006.01) A61K 31/535 (2006.01) C07D 263/57 (2006.01) C07D 413/04 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2116337

ABSTRACT An oxazolidone derivative represented by the following general formula (I) or a pharmacologically acceptable salt thereof which has a monoamine oxidase inhibition effect: Image (I) {wherein A and B each represents a nitrogen atom, a sulfur atom or an oxygen atom, with the proviso that at least one of A and B must be a nitrogen atom, R1 represents a group such as a group represented by the formula: Image (in which n and m each represents 0 or an integer of 1 to 4, and R3 and R4 each represents a hydrogen atom, a hydroxyl group, a lower alkyl group, etc.), a group represented by the formula: Image (in which p and q each represents 0 or an integer of 1 to 4 and X represents an oxygen atom, sulfur atom, - 74 - etc.) and a group represented by the formula: Image (in which R5 and R6 each represents a hydrogen atom or a group such as a cyanoalkyl group, or R5 and R6 may form a ring together with the nitrogen atom to which they are bonded), R2 represents a hydrogen atom or a lower alkyl group, and the bond represented by Image represents a single or double bond}. - 75 -

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