Oxazolinoazetidinylbutyric acid derivatives

Details Oxazolinoazetidinylbutyric acid derivatives Oxazolinoazetidinylbutyric acid derivatives

C - Chemistry, Metallurgy

07

D

260/242, 260/298

C07D 498/04 (2006.01) C07D 205/085 (2006.01) C07D 505/00 (2006.01)

Patent

CA 1111854

OXAZOLINOAZETIDINYLBUTYRIC ACID DERIVATIVES ABSTRACT New intermediates (I) for preparing a potent antibacterial; 1-oxadethiacephalosporin, are shown by the following formula Image Image (I) (II) (wherein R is a group of acyl-minus-carbonyl derived from a carboxylic or carbonic acid; COB is carboxy or protected carboxy; X is hydrogen or a nucleophilic group; Y is a nucleophilic group; and z is a leaving group) and prepared from the corresponding exomethylene compound (II) by addition of a compound of formula: Y-Z (in which Y and Z are as defined above).

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