Oxazolyl-pyrazole derivatives as kinase inhibitors

Details Oxazolyl-pyrazole derivatives as kinase inhibitors Oxazolyl-pyrazole derivatives as kinase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 498/04 (2006.01) A61K 31/423 (2006.01) A61K 31/437 (2006.01) A61P 25/28 (2006.01) A61P 31/12 (2006.01) A61P 35/00 (2006.01) A61P 37/00 (2006.01) C07D 413/04 (2006.01) C07D 413/14 (2006.01) C40B 40/04 (2006.01) C12N 9/12 (2006.01) C12N 9/99 (2006.01)

Patent

CA 2437260

Compounds which are oxazolyl-pyrazole derivatives, as defined in the specification, and pharmaceutically acceptable salts thereof; are useful in the treatment of diseases caused by and/or associated with an altered protein kinase activity such as cancer, cell proliferative disorders, viral infections, autoimmune diseases and neurodegenerative disorders.

L'invention concerne des composés qui sont des dérivés oxazolyl-pyrazole, définis dans les spécifications, ainsi que des sels de ces composés acceptables sur le plan pharmaceutique. Ces composés sont utiles dans le traitement de maladies provoquées par et/ou associées à une activité déficiente de protéine kinase, telle que le cancer, à des troubles de prolifération cellulaire, à des infections virales, à des maladies auto-immunes et à des troubles neurodégénératifs.

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