Oxicam derivatives as inhibitors of 5-lipoxygenase

C - Chemistry – Metallurgy – 07 – D

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C07D 417/04 (2006.01) A61K 31/54 (2006.01) C07D 417/14 (2006.01)

Patent

CA 1277318

Abstract Certain substituted-4-hydroxy-(or 4-acyloxy-)2H- 1,2-benzothiazine l,l-dioxides having at the 3-position a 2-substituted-1,3,4-oxadiazol-5-yl, a 2-substituted- tetrazol-5-yl or a l-substituted-tetrazol-5-yl group useful as selective 5-lipoxygenase pathway inhibitors; and methods for their preparation.

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