Oxidation of 2-arylpropanals

Details Oxidation of 2-arylpropanals Oxidation of 2-arylpropanals

C - Chemistry, Metallurgy

07

C

260/507.1, 260/5

C07C 51/255 (2006.01) C07C 51/235 (2006.01) C07C 57/30 (2006.01)

Patent

CA 1272737

ABSTRACT OF THE DISCLOSURE 2-(4-isobutylphenol) propionic acld (*ibuprofen and other 2-aryl propionic acids useful as analgesic and anti-inflammatory agents, are produced by oxidation of the corresponding 2-aryl propionaldehydes with oxygen in the presence of soluble manganese or cobalt catalysts, with high selectivities with soluble manganese salts, or with soluble cobalt salts along with sodium salts. *Trademark

523680

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