Oxidation process using periodic acid

Details Oxidation process using periodic acid Oxidation process using periodic acid

C - Chemistry, Metallurgy

07

D

C07D 405/04 (2006.01)

Patent

CA 2327926

The present invention relates to a periodic acid oxidation which converts the penultimate intermediate bearing a primary alcohol to the target endothelin antagonist compound of Formula (I) having a carboxylic acid.

L'invention concerne une oxydation à l'acide périodique permettant de convertir l'avant-dernier intermédiaire portant un alcool primaire en composé ciblé antagoniste d'endothéline représenté par la formule (I) et possédant un acide carboxylique.

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