Oxidative degradation products of atorvastatin calcium

Details Oxidative degradation products of atorvastatin calcium Oxidative degradation products of atorvastatin calcium

C - Chemistry, Metallurgy

07

D

C07D 498/14 (2006.01) A61K 31/40 (2006.01) A61P 9/00 (2006.01) C07D 207/40 (2006.01) C07D 303/48 (2006.01) C07D 493/04 (2006.01)

Patent

CA 2573969

The present invention relates to oxidative degradation products of atorvastatin calcium and the process of the preparation thereof. The present invention also relates to atorvastatin calcium substantially free of oxidative degradation products and the pharmaceutical compositions containing such atorvastatin calcium.

L'invention concerne des produits de dégradation oxydante du calcium d'atorvastatine et le procédé de préparation de ceux-ci. L'invention concerne également du calcium d'atorvastatine sensiblement exempt de produits de dégradation oxydante et les compositions pharmaceutiques renfermant un tel calcium d'atorvastatine.

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