Oxidized variants of gm-csf

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 14/535 (2006.01) A61K 38/19 (2006.01) C07K 1/107 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2072587

2072587 9110684 PCTABS00006 Biologically active oxidized variants of granulocyte-macrophage colony stimulating factor (GM-CSF) are provided in which one or more methionine residues are oxidized. Methods are also provided for making and characterizing such variants.

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