Oxim derivatives as hsp90 inhibitors

Details Oxim derivatives as hsp90 inhibitors Oxim derivatives as hsp90 inhibitors

C - Chemistry, Metallurgy

07

D

C07D 239/84 (2006.01) A61K 31/517 (2006.01) A61K 31/519 (2006.01) A61P 35/00 (2006.01) C07D 487/04 (2006.01)

Patent

CA 2713658

The invention relates to HSP90 inhibiting compounds consisting of the formula: (I) wherein the variables are as defined herein. The invention also relates to pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.

L'invention concerne des composés inhibiteurs de HSP90 répondant à la formule (I) dans laquelle les variables sont telles que définies par le présentes. L'invention concerne également des compositions pharmaceutiques, des kits et des articles de fabrication comportant de tels composés ; des procédés et des intermédiaires utiles pour préparer les composés, et des procédés d'utilisation desdits composés.

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