Oxime ethers, their preparation and pharmaceutical...

C - Chemistry – Metallurgy – 07 – D

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C07D 233/64 (2006.01) C07D 215/12 (2006.01) C07D 233/54 (2006.01) C07D 235/14 (2006.01) C07D 237/08 (2006.01) C07D 277/28 (2006.01) C07D 277/64 (2006.01) C07D 471/04 (2006.01)

Patent

CA 1127169

Abstract of the disclosure Oxime ether derivatives of the formula (I): Image (I) wherein Het is a monocyclic heteroaromatic group containing two hetero atoms at least one of which is nitrogen, or a bicyclic heteroaromatic group containg one or two hetero atoms at least one of which is nitrogen, Ar is a phenyl or a 5- or 6-membered monocyclic heteroaromatic group, and R is an alkyl, alkenyl, alkynyl, cyanoalkyl, carbamidoalkyl or aminoalkyl group, or N-oxides thereof, have anti-ulcer activity in the gastro-intestinal tract of mammals.

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