Oxindole compounds

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 405/06 (2006.01) A61K 31/404 (2006.01) A61K 31/551 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01) C07D 405/14 (2006.01)

Patent

CA 2729745

The invention provides compounds that inhibit PIM kinases and F1t3 kinase, and compositions containing such compounds. These compounds and compositions are useful for treating proliferative disorders such as cancer, as well as other kinase-associated conditions including inflammation.

L'invention concerne des composés inhibiteurs PIM de kinases et de Flt3 kinase, et des compositions contenant de tels composés. Ces composés et compositions sutilisent pour traiter des troubles prolifératifs comme le cancer, ainsi que d'autres états associés à une kinase, y compris une inflammation.

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