Oxindole oxazolidinones as antibacterial agents

Details Oxindole oxazolidinones as antibacterial agents Oxindole oxazolidinones as antibacterial agents

C - Chemistry, Metallurgy

07

D

C07D 413/04 (2006.01) A61K 31/422 (2006.01) A61P 31/04 (2006.01)

Patent

CA 2575702

The present invention relates to novel oxazolidinones derivatives of oxindoles of formula I or a pharmaceutically acceptable salt thereof wherein: Y1 is CH or CF; R1 is -C1-4alkyl, optionally substituted with a fluoro atom, or R1 is - C3-5cycloalkyl; and R2 is -C1-2alkyl. These compounds are useful as antibacterial agents.

La présente invention concerne de nouveaux dérivés oxazolidinones d'oxindoles de formule I ou un sel pharmaceutiquement acceptable de ces derniers. Dans ladite formule, Y1 représente CH ou CF; R1 représente alkyle C1-4, éventuellement substitué par un atome de fluor, ou R1 représente cycloalkyle C3-5 ; et R2 représente alkyle C1-2. Lesdits composés sont utiles en tant qu'agents antibactériens.

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