Oxy-vanadium (iv) complexes having spermicidal activity

Details Oxy-vanadium (iv) complexes having spermicidal activity Oxy-vanadium (iv) complexes having spermicidal activity

A - Human Necessities

61

K

A61K 31/28 (2006.01) C07F 9/00 (2006.01)

Patent

CA 2318162

Organometallic oxovanadium (IV) complexes having potent spermicidal activity, particularly those having at least one bidentate ligand. Preferred compounds are stable oxovanadium (IV) complexes having, as ancillary ligands linked via nitrogen or oxygen-metal bonds, bis and/or mono-1,10-phenanthroline; 2,2'- bipyridyl; or 2-hydroxyacetophenone.

L'invention concerne des complexes organométalliques d'oxovanadium (IV) présentant une forte activité spermicide, en particulier les complexes comportant au moins un ligand bidenté. Les composés préférés sont des complexes d'oxovanadium stables, comprenant, comme ligands auxiliaires liés via des liaisons azote ou oxygène-métal, bis et/ou mono-1,10-phénanthroline; 2,2'-bipyridyle; ou 2-hydroxyacétophénone.

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