C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 319/16 (2006.01) A61K 31/335 (2006.01) A61K 31/36 (2006.01) C07D 317/46 (2006.01) C07D 317/64 (2006.01) C07D 319/20 (2006.01) C07D 321/00 (2006.01) C07D 405/04 (2006.01) C07D 407/04 (2006.01) C07D 407/08 (2006.01)
Patent
CA 2341890
The present invention relates to oxygen-containing heterocyclic compounds represented by the following formula (I): (see formula I) wherein m represents an integer of 0 to 4; R1, R2, R3 and R4 independently represent a hydrogen atom, substituted or unsubstituted lower alkyl, etc.; R5 represents substituted or unsubstituted lower alkoxy etc .; R6 represents a hydrogen atom etc.; and Y represents the following formula (II): (see formula II) wherein R9 represents cyano etc., R10 represents a hydrogen atom etc., R11 represents carboxy etc., and R12 represents a hydrogen atom etc.; and the like; or pharmaceutically acceptable salts thereof.
L'invention concerne des composés hétérocycliques oxygénés représentés par la formule (I) ou des sels pharmaceutiquement acceptables de ces composés. Dans ladite formule, m est un entier allant de 0 à 4; R<1>, R<2>, R<3> et R<4> sont identiques ou différents, représentant chacun hydrogène, alkyle inférieur éventuellement substitué, etc.; R<5> est alcoxy inférieur éventuellement substitué, etc.; R<6> est hydrogène, etc.; et Y est, par exemple, la formule (II). Dans cette formule, R<9> est cyano, etc.; R<10> est hydrogène, etc.; R<11> est carboxy, etc.; et R<12> est hydrogène, etc.
Manabe Haruhiko
Masuda Yoshiaki
Miki Ichiro
Ohshima Etsuo
Yanagawa Koji
Goudreau Gage Dubuc
Kyowa Hakko Kogyo Co. Ltd.
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