A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 45/00 (2006.01) A61K 31/02 (2006.01) A61K 33/00 (2006.01) A61K 33/32 (2006.01) A61K 33/40 (2006.01) A61K 38/42 (2006.01) A61K 38/44 (2006.01) A61K 45/06 (2006.01) A61P 31/00 (2006.01) A61P 31/04 (2006.01)
Patent
CA 2480141
Oxygenating agents are used in the present invention for the novel purpose of treating microbial infections. The invention takes advantage of the fact that the increase in tissue pO2 produced thereby can enhance the efficacy of the body's own antimicrobial defenses (including tissue repair), while also improving the efficacy of adjunctive agents that may be co-administered, such as antimicrobial agents, antioxidants, cytokine modulators, endotoxin antagonists and growth factors. The oxygenating agents of the present invention achieve the desired increased pO2 in the tissues without having to resort to the risks and expenses of hyperbaric oxygen therapy (HBO). The oxygenating agents can be administered systemically, regionally, or topically.
L'invention porte sur une nouvelle utilisation d'agents oxygénants pour traiter les infections microbiennes, et tire parti du fait qu'un accroissement ainsi produit de la pO¿2? dans les tissus renforce les défenses antimicrobiennes propres du corps (dont la réparation de tissus) tout en augmentant l'efficacité d'agents adjuvants co-administrés tels que des antimicrobiens, des antioxydants, des modulateurs de la cytokine, des antagonistes des endotoxines et des facteurs de croissance. Lesdits agents oxygénant, qui produisent l'accroissement désiré de la pO¿2? dans les tissus sans présenter les risques et les coûts de l'oxygénothérapie hyperbare (HBO), peuvent s'administrer systémiquement, localement ou topiquement.
Carlton Richard M.
Galpin Jeffrey E.
Carlton Richard M.
Exponential Biotherapies Inc.
Galpin Jeffrey E.
Gowan Intellectual Property
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