Oxyindole derivatives with motilin receptor agonistic activity

C - Chemistry – Metallurgy – 07 – D

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Details

C07D 401/14 (2006.01) A61K 31/454 (2006.01) A61K 31/497 (2006.01) A61P 1/04 (2006.01) A61P 1/06 (2006.01) A61P 43/00 (2006.01) C07D 401/04 (2006.01)

Patent

CA 2750699

The present invention relates to novel oxyindole derivatives of formula (I) or a pharmaceutically acceptable salt thereof, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of various disorders which are mediated via the motilin receptor (GPR38).

La présente invention concerne de nouveaux dérivés d'oxyindole de formule (I) ou un sel pharmaceutiquement acceptable de ceux-ci, des procédés pour leur préparation, des compositions pharmaceutiques les contenant et leur utilisation dans le traitement de divers troubles qui sont induits par le récepteur de la motiline (GPR38).

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