Oxysulfonyl urea acat inhibitors

C - Chemistry – Metallurgy – 07 – C

Patent

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C07C 311/54 (2006.01) A61K 31/64 (2006.01) C07C 307/02 (2006.01) C07D 213/56 (2006.01) C07D 295/215 (2006.01) C07D 307/54 (2006.01) C07D 333/24 (2006.01)

Patent

CA 2094808

Novel compounds of formula (I), wherein R is hydrogen, a straight or branched alkyl group having from 1 to 8 carbon at- oms or benzyl; wherein each of R1 and R2 is hydrogen, an aralkyl group, a straight or branched hydrocarbon group having from 1 to 20 carbon atoms and may be saturated or unsaturated, an alkyl group of from 1 to 6 carbon atoms wherein the terminal carbon is substituted, the group -(CH2)p-Q wherein p is zero to three and Q is a 5- or 6-membered monocyclic or fused bicyclic heterocycle, phenyl or NR1R2 taken together form a monocyclic heterocyclic ring, and R3 is phenyl, substitut- ed phenyl, naphthyl, substituted naphthyl, -(CH2)p-Q wherein p and Q are as defined above, an aralkyl group or a straight or branched hydrocarbon group having from 1 to 20 carbon atoms and being straight or branched.

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