C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) C07K 14/47 (2006.01) C12Q 1/68 (2006.01) G01N 33/68 (2006.01)
Patent
CA 2222208
The present invention provides a method to identify new proteins associating to the p53 tumor suppressor protein as well as elucidating the genes encoding said proteins, with some examples of cDNAs isolated this way. It also relates to the results of said method, which are novel proteins having affinity for p53, as well as genes and other nucleic acid molecules encoding these novel proteins. In particular the invention also provides such a novel protein and its encoding sequences, which protein has homology with the Mdm2 protein and which therefore has been designated as Mdmx.
La présente invention concerne un procédé pour identifier de nouvelles protéines se fixant sur la protéine p53 suppressive des tumeurs, ainsi que pour identifier les gènes codant pour ces protéines. Quelques exemples d'ADNc isolés par ce procédé sont présentés. L'invention concerne également le résultat de ce procédé, en l'occurrence des protéines nouvelles présentant une affinité pour p53, ainsi que des gènes et d'autres molécules d'acide nucléique codant pour ces nouvelles protéines. L'invention concerne en outre une nouvelle protéine et les séquences codant pour celle-ci, laquelle protéine est un homologue de la protéine Mdm2 et a donc été dénommée Mdmx.
Jochemsen Aart-Gerrit
Shvarts Avraam
Vander Eb Alex Jan
Borden Ladner Gervais Llp
Crucell Holland B.v.
Introgene B.v.
Rijksuniversiteit Leiden
LandOfFree
P-53 binding protein called mdmx and encoding sequences for... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with P-53 binding protein called mdmx and encoding sequences for..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and P-53 binding protein called mdmx and encoding sequences for... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1439793