P-aminophenols, derivatives thereof and method of use

Details P-aminophenols, derivatives thereof and method of use P-aminophenols, derivatives thereof and method of use

C - Chemistry, Metallurgy

07

C

167/246, 260/557

C07C 217/84 (2006.01) A61K 31/22 (2006.01) C07C 219/34 (2006.01) C07C 233/12 (2006.01) C07C 233/16 (2006.01)

Patent

CA 1303057

QA192 Abstract p-AMINOPHENOLS, DERIVATIVES THEREOF AND METHOD OF USE p-Aminophenols are provided having the structure Image wherein m is 0, 1 or 2; n is 0, 1, 2 or 3; R1 and R2 may be the same or different and are H, hydroxy or alkoxy; R3 is H, lower alkyl, alkanoyl or aroyl; and R4 is H, lower alkyl or alkanoyl, and including acid-addition salts thereof. These compounds are useful as inhibitors of leukotriene production and as such are useful as antiallergy, anti-inflammatory and anti-psoriatic agents.

537924

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