G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/53 (2006.01) G01N 33/574 (2006.01) G01N 33/577 (2006.01) G01N 35/00 (2006.01)
Patent
CA 2728449
The present disclosure relates to, among other things, methods for determining whether a subject receiving treatment with a drug has obtained an efficacious blood level of the drug. Moreover, the present disclosure also relates to methods of determining whether a subject predisposed to or suffering from a disease will benefit from treatment with a drug, and the response of a subject receiving treatment (e.g., such as for cancer) by monitoring biomarkers of angiogenesis. In particular, the disclosure relates to P/GF-1 companion diagnostic methods and products.
La présente invention concerne, entre autres, des procédés de détermination pour savoir si un sujet recevant un traitement avec un médicament a obtenu une concentration sanguine efficace du médicament. En outre, la présente invention concerne également des procédés de détermination pour savoir si un sujet prédisposé ou souffrant d'une maladie bénéficiera d'un traitement avec un médicament, ainsi que la réponse d'un sujet recevant un traitement (par exemple contre le cancer) en surveillant des biomarqueurs d'angiogenèse. En particulier, l'invention concerne des procédés de diagnostic par compagnon P/GF-1 et des produits.
Datwyler Saul
Hawksworth David J.
Laird Don M.
Lesniewski Richard R.
Mckeegan Evelyn Mary
Abbott Laboratories
Torys Llp
LandOfFree
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