P. gingivalis antigenic composition

A - Human Necessities – 61 – K

Patent

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Details

A61K 38/16 (2006.01) A61K 39/02 (2006.01) A61K 39/40 (2006.01) A61P 31/04 (2006.01) C07K 14/195 (2006.01) C07K 16/12 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2395423

The present invention provides an antigenic composition, the composition comprising at least one recombinant protein. The recombinant protein comprises at least one epitope. The epitope is reactive with an antibody which is reactive with a polypeptide having the sequence set out in SEQ. ID. NO. 3 or SEQ. ID. NO. 5. The invention also provides methods and compositions for the production of the recombinant protein. Also provided are methods for the diagnosis, treatment and prevention of P. gingivalis infection.

L'invention concerne une composition antigénique qui comporte au moins une protéine recombinée. La protéine recombinée comporte au moins un épitope. L'épitope réagit à un anticorps, qui réagit lui-même à un polypeptide présentant la séquence décrite dans SEQ. ID. NO. 3 ou SEQ. ID. NO. 5. L'invention concerne aussi des procédés et des compositions utiles pour produire la protéine recombinée. L'invention concerne également des procédés utiles pour diagnostiquer, traiter et prévenir une infection à P. gingivalis.

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