P-rex1, a ptdins (3, 4, 5) p3- g-beta-gamma-regulated...

Details P-rex1, a ptdins (3, 4, 5) p3- g-beta-gamma-regulated... P-rex1, a ptdins (3, 4, 5) p3- g-beta-gamma-regulated...

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A01K 67/027 (2006.01) C07H 21/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C07K 19/00 (2006.01) C12P 21/02 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2479907

A novel protein useful as an anti-inflammatory target is described. Methods of making the protein, and use of the protein in assays for identification of anti-inflammatory agents are described. Methods of making knockout mice for the gene encoding the protein are also described.

La présente invention concerne une nouvelle protéine qui convient comme cible anti-inflammatoire. Cette invention concerne aussi des procédés de fabrication de cette protéine et d'utilisation de celle-ci dans des dosages destinés à identifier des agents anti-inflammatoires. Cette invention concerne enfin des techniques de génération de souris <=knock-out>= pour le gène codant la protéine.

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