P153 and p156 antigens for the immunodiagnosis of canine and...

C - Chemistry – Metallurgy – 12 – N

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C12N 5/00 (2006.01) A01N 43/04 (2006.01) A61K 39/02 (2006.01) C07H 21/02 (2006.01) C07H 21/04 (2006.01) C07K 14/29 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2504762

Sequences encoding two immunoreactive glycoproteins were cloned from Ehrlichia canis (p153 gene) and Ehrlichia chaffeensis (p156 gene). These two glycoproteins are species-specific immunoreactive orthologs that are useful as subunit vaccines and for serologic and molecular diagnostics for E. canis and E. chaffeensis.

L'invention concerne des séquences qui codent deux glycoprotéines immunoréactives qui ont été clonées à partir de Ehrlichia canis (gène p153) et de Ehrlichia chaffeensis (gène p156). Ces deux glycoprotéines sont des orthologues immunoréactifs propres à des espèces et utiles en tant que vaccins de sous-unités et pour les diagnostics moléculaires et sérologiques de E. canis et E. chaffeensis.

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