P2x3, receptor antagonists for treatment of pain

Details P2x3, receptor antagonists for treatment of pain P2x3, receptor antagonists for treatment of pain

C - Chemistry, Metallurgy

07

D

C07D 495/04 (2006.01) A61K 31/415 (2006.01) A61K 31/4162 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2755768

The subject invention relates to novel P2X3 receptor antagonists that play a critical role in treating disease states associated with pain, in particular peripheral pain, inflammatory pain, or tissue injury pain that can be treated using a P2X3 receptor subunit modulator.

L'invention concerne de nouveaux antagonistes du récepteur P2X3 qui jouent un rôle important dans le traitement de la douleur associée à des états pathologiques, notamment la douleur périphérique, la douleur inflammatoire ou la douleur de lésion tissulaire qui peut être traitée à l'aide d'un modulateur des sous-unités du récepteur P2X3.

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