C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 213/89 (2006.01) A61K 31/41 (2006.01) A61K 31/44 (2006.01) A61K 31/505 (2006.01) A61P 25/00 (2006.01) C07C 235/42 (2006.01) C07D 213/56 (2006.01) C07D 213/61 (2006.01) C07D 239/26 (2006.01) C07D 249/08 (2006.01) C07D 271/06 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 413/14 (2006.01)
Patent
CA 2703909
The subject invention relates to novel P2X3 receptor antagonists that play a critical role in treating disease states associated with pain, in particular peripheral pain, inflammatory pain, or tissue injury pain that can be treated using a P2X3 receptor subunit modulator.
La présente invention concerne de nouveaux antagonistes du récepteur P2X3 qui jouent un rôle critique dans le traitement d'états pathologiques associés à la douleur, en particulier la douleur périphérique, la douleur inflammatoire ou la douleur associée à des lésions cellulaires pouvant être traitées à l'aide d'un modulateur de sous-unité du récepteur P2X3.
Burgey Christopher S.
Deng Zhengwu James
Nguyen Diem N.
Paone Daniel V.
Potteiger Craig M.
Merck Sharp & Dohme Corp.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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