P2x3, receptor antagonists for treatment of pain

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 471/04 (2006.01) A61K 31/437 (2006.01) A61K 31/4439 (2006.01) A61P 25/00 (2006.01) C07D 401/12 (2006.01) C07D 413/12 (2006.01)

Patent

CA 2755680

The subject invention relates to novel P2X3 receptor antagonists that play a critical role in treating disease states associated with pain, in particular peripheral pain, inflammatory pain, or tissue injury pain that can be treated using a P2X3 receptor subunit modulator.

L'invention concerne de nouveaux antagonistes du récepteur P2X3 qui jouent un rôle important dans le traitement de la douleur associée à des états pathologiques, notamment la douleur périphérique, la douleur inflammatoire ou la douleur de lésion tissulaire qui peut être traitée à l'aide d'un modulateur des sous-unités du récepteur P2X3.

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