P38 map kinase inhibitors

Details P38 map kinase inhibitors P38 map kinase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 401/12 (2006.01) A61K 31/415 (2006.01) A61P 11/00 (2006.01) A61P 29/00 (2006.01) C07D 401/14 (2006.01)

Patent

CA 2746357

The invention relates to compounds of formula (I): or a pharmaceutically acceptable salt thereof, including all stereoisomers, tautomers and isotopic derivatives thereof, which are inhibitors of p38 mitogen-activated protein kinase enzymes (referred to herein as p38 MAP kinase inhibitors), particularly the alpha and gamma kinase sub-types thereof, and their use in therapy, including in pharmaceutical combinations, especially in the treatment of inflammatory diseases, including inflammatory diseases of the lung, such as COPD.

Cette invention concerne des composés de formule (I) : ainsi qu'un sel de ces composés acceptable au plan pharmaceutique, qui sont des inhibiteurs de protéine kinase activée par mitogène par p38 (ou inhibiteurs de kinase map 38), en particulier de sous-types alpha et gamma kinase, et leur utilisation thérapeutique, ainsi que des compositions pharmaceutiques utilisées en particulier pour le traitement de maladies inflammatoires, notamment du poumon telles que les broncho-pneumopathies chroniques obstructives (BPCO).

Affiliated with

Also associated with

Rating

P38 map kinase inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with P38 map kinase inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and P38 map kinase inhibitors will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-2029757