P38 map kinase inhibitors and methods for using the same

Details P38 map kinase inhibitors and methods for using the same P38 map kinase inhibitors and methods for using the same

C - Chemistry, Metallurgy

07

D

C07D 231/56 (2006.01) A61K 31/416 (2006.01) A61P 25/00 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2620257

Compounds of formula Ia or Ib: wherein X and Y are nitrogen or CRe, and R1, R2, R3, R4 and R5 are as defined herein. Also disclosed are methods of making the subject compounds and methods of using the compounds for treatment of p38- mediated diseases.

L'invention concerne des composés représentés par la formule Ia ou Ib, dans laquelle X et Y représentent azote ou CRe, et R1, R2, R3, R4 et R5 sont tels que définis dans la description. L'invention concerne également des procédés de préparation des composés de l'invention ainsi que des procédés d'utilisation des composés pour le traitement de maladies médiées par p38.

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