P38map kinase inhibitors

Details P38map kinase inhibitors P38map kinase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 417/04 (2006.01) A61K 31/4439 (2006.01) A61K 31/444 (2006.01) A61K 31/5377 (2006.01) A61P 1/04 (2006.01) A61P 1/16 (2006.01) A61P 3/10 (2006.01) A61P 7/06 (2006.01) A61P 7/08 (2006.01) A61P 9/04 (2006.01) A61P 9/10 (2006.01) A61P 11/00 (2006.01) A61P 11/06 (2006.01) A61P 13/12 (2006.01) A61P 17/04 (2006.01) A61P 19/02 (2006.01) A61P 19/10 (2006.01) A61P 21/00 (2006.01) A61P 25/16 (2006.01) A61P 25/28 (2006.01) A61P 29/00 (2006.01) A61P 31/06 (2006.01) A61P 31/12 (2006.01) A61P 35/00 (2006.01) A61P 37/0

Patent

CA 2381215

1,3-Thiazole compounds substituted by optionally substituted pyridyl at the 5- position have excellent effects of inhibiting p38MAP kinase and inhibiting TNF- .alpha. production.

Cette invention se rapporte à des composés de 1,3-thiazole substitués par pyridyle éventuellement substitué dans la position 5, ces composés ayant d'excellents effets d'inhibition de la p38MAP kinase et d'inhibition de la production de TNF-.alpha..

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