P450 enzymes, nucleic acids encoding them and methods of...

Details P450 enzymes, nucleic acids encoding them and methods of... P450 enzymes, nucleic acids encoding them and methods of...

C - Chemistry, Metallurgy

12

N

C12N 15/53 (2006.01) A01H 5/00 (2006.01) A01H 5/10 (2006.01) A01K 67/02 (2006.01) A61K 31/7088 (2006.01) A61K 48/00 (2006.01) C07H 21/00 (2006.01) C07K 16/40 (2006.01) C07K 19/00 (2006.01) C12N 5/12 (2006.01) C12N 9/02 (2006.01) C12N 11/00 (2006.01) C12N 15/09 (2006.01) C12N 15/10 (2006.01) C12N 15/63 (2006.01) C12N 15/82 (2006.01) C12N 15/85 (2006.01) C12P 19/34 (2006.01) C12P 21/02 (2006.01) C12P 21/08 (2006.01) C12Q 1/02 (2006.01) C12Q 1/26 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/573 (

Patent

CA 2456210

The invention is directed to polypeptides having P450 activity, polynucleotides encoding the polypeptides, antibodies that bind to these polypeptides, and methods for making and using these polynucleotides and polypeptides. The P450 enzymes can be used to catalyze the hydrolysis of epoxides and arene oxides to their corresponding diols.

L'invention concerne des polypeptides à activité P450, des polynucléotides codant pour ces polypeptides, des anticorps qui se fixent sur ces polypeptides, ainsi que des procédés de fabrication et d'utilisation de ces polynucléotides et polypeptides. Les enzymes P450 peuvent servir de catalyseurs dans l'hydrolyse d'époxydes et d'oxydes aréniques en diols correspondants.

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