P53 regulatory protein called rb18a and uses thereof

C - Chemistry – Metallurgy – 12 – N

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Details

C12N 15/12 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 5/10 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2315275

This invention relates to a new protein called RB18A for "Recognized By PAb1801 moAntibody", which is a p53 regulatory protein, to the nucleotide sequence encoding said protein, and to the diagnostic and therapeutic applications thereof, in particular for the diagnosis, prevention or treatment of neoplasia.

Cette invention concerne une nouvelle protéine appelée RB18A ("Reconnu par l'anticorps monoclonal PAb1801"), laquelle est une protéine régulatrice de p53, la séquence nucléotidique codant cette protéine, et ses applications diagnostiques et thérapeutiques. Cette protéine convient particulièrement au diagnostic, à la prévention et au traitement de la néoplasie.

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