P66-shc as predictive marker in cancer treatment

G - Physics – 01 – N

Patent

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G01N 33/574 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2627535

The present invention provides a method for predicting whether an individual (e.g., patient) will benefit from a (one or more) treatment for cancer comprising determining the amount of p66-Shc present in cancerous cells or precancerous cells (e.g., displasia) of the individual. If the amount of p66- Shc present in the cells of the individual is lower than the amount of p66-Shc in a control, then the individual will likely benefit from the treatment.

La présente invention concerne un procédé pour prévoir si une personne (par exemple le patient) bénéficiera d'un (ou de plusieurs) traitement du cancer comprenant la détermination du nombre de p66-Shc présents dans les cellules cancéreuses ou précancéreuses (par exemple dysplasie) de la personne. Si la quantité de p66-Shc présents dans les cellules de la personne est inférieure à la quantité de p66-Shc dans un contrôle, la personne bénéficiera alors probablement du traitement.

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