P70s6 kinase modulators and method of use

Details P70s6 kinase modulators and method of use P70s6 kinase modulators and method of use

C - Chemistry, Metallurgy

07

D

C07D 413/00 (2006.01) A01N 43/40 (2006.01) A01N 43/54 (2006.01) A01N 43/66 (2006.01) A61K 31/535 (2006.01) C07D 213/84 (2006.01) C07D 239/02 (2006.01) C07D 251/48 (2006.01)

Patent

CA 2541989

The invention provides compounds and methods for inhibition of kinases, more specifically p70S6 kinases. The invention provides compounds for modulating protein kinase enzymatic activity for modulating cellular activities such as proliferation, differentiation, programmed cell death, migration, chemoinvasion and metabolism. Compounds of the invention inhibit, regulate and/or modulate kinase receptor signal transduction pathways related to the changes in cellular activities as mentioned above, and the invention includes compositions which contain these compounds, and methods of using them to treat kinase-dependent diseases and conditions.

L'invention concerne des composés et des procédés permettant d'inhiber des kinases, plus spécifiquement les p70S6 kinases. Elle concerne des composés permettant de moduler l'activité enzymatique de protéines kinases afin de moduler des activités cellulaires telles que la prolifération, la différenciation, la mort cellulaire programmée, la migration, le chimiotactisme et le métabolisme. Les composés de l'invention inhibent, régulent et/ou modulent les voies de transduction du signal des récepteurs de kinases, lesdites voies étant liées à des changements dans les activités cellulaires mentionnées. L'invention comprend des compositions contenant ces composés, et des procédés d'utilisation de celles-ci pour traiter des maladies et des états pathologiques dépendant des kinases.

Affiliated with

Also associated with

Rating

P70s6 kinase modulators and method of use does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with P70s6 kinase modulators and method of use, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and P70s6 kinase modulators and method of use will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1997417