Packing materials for chromatographic use and a method for...

B - Operations – Transporting – 01 – D

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182/2, 252/23

B01D 15/08 (2006.01) B01J 20/32 (2006.01)

Patent

CA 1204720

ABSTRACT OF THE DISCLOSURE A packing material for chromatographic use com- prising an inorganic carrier having hydroxyl groups at the surface thereof having grafted thereon an organosilane derivative selected from the group consisting of a urea derivative obtained by reacting an optically active iso- cyanate with an aminoalkylsilane, an N-carbamoyl amino acid derivative obtained by reacting an optically active amino acid carbamoylated by isocyanate with an aminoalkylsilane and an O-carbamoyl hydroxy acid derivative obtained by reacting an optically active hydroxy acid carbamoylated by isocyanate with an aminoalkylsilane is disclosed. This packing material is useful as a packing material for liquid chromatography analysis which comprises separating and analyzing an enantiomer mixture of a compound having an -OH group, a -CONH- group, a -CO?- group, a -COO- group, an -NHCOO- group, an -NHCONH- group or an -NHCO?- group bonded to an asymmetric carbon atom thereof.

437948

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