Paks as modifiers of the chk pathway and methods of use

Details Paks as modifiers of the chk pathway and methods of use Paks as modifiers of the chk pathway and methods of use

G - Physics

01

N

G01N 33/00 (2006.01) A61K 49/00 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2497801

Human PAK genes are identified as modulators of the CHK pathway, and thus are therapeutic targets for disorders associated with defective CHK function. Methods for identifying modulators of CHK, comprising screening for agents that modulate the activity of PAK are provided.

L'invention concerne des gènes PAK humains identifiés en tant que modulateurs de la voie de CHK et ainsi des cibles thérapeutiques pour des troubles associés à un dysfonctionnement de la CHK. L'invention concerne des procédés d'identification des modulateurs de CHK, comprenant le criblage d'agents qui modulent l'activité des PAK.

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