C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 319/08 (2006.01) A61K 31/357 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2622674
Embodiments of the present invention relate to inhibitors of thioredoxin. Certain embodiments relate to palmarumycin based compounds and methods of using the same. Such compounds may be useful in inhibiting the overexpression of thioredoxin, inhibiting tumor growth and treating cancer.
La présente invention concerne des inhibiteurs de thiorédoxine. Dans certains modes de réalisation, l'invention concerne des composés à base de palmarumycine et leurs procédés d'utilisation. Ces composés peuvent servir à inhiber l'expression excessive de thiorédoxine, à inhiber une croissance tumorale, et à traiter le cancer.
Powis Garth
Wipf Peter
Arizona Board Of Regents Acting On Behalf Of The University Of Arizona
Borden Ladner Gervais Llp
University Of Pittsburgh
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