G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/53 (2006.01) G01N 33/543 (2006.01) G01N 33/577 (2006.01)
Patent
CA 2719385
A biomarker for pancreatic beta-cell mass comprising measuring the levels of CFC1 in the serum of a subject is described. The biomarker provides a noninvasive means for measuring pancreatic beta cell mass that is particularly useful for monitoring the efficacy of treatments for metabolic disorders such as Type I or Type II diabetes, including pancreatic islet cell transplantations.
La présente invention concerne un biomarqueur pour la masse de cellules bêta pancréatiques comprenant la mesure des taux de CFC1 dans le sérum d'un sujet. Le biomarqueur constitue un moyen non invasif pour mesurer la masse de cellules bêta pancréatiques qui est particulièrement utile pour surveiller lefficacité de traitements pour des troubles métaboliques tels que le diabète de type I ou de type II, comprenant des transplantations de cellules dîlots pancréatiques.
Howard Andrew
Thornberry Nancy
Zhou Yun-Ping
Merck Sharp & Dohme Corp.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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