Pancreatic islet-like cells

Details Pancreatic islet-like cells Pancreatic islet-like cells

C - Chemistry, Metallurgy

12

N

C12N 5/0786 (2010.01) C12N 5/071 (2010.01) A61K 35/39 (2006.01) A61P 3/10 (2006.01)

Patent

CA 2651326

The generation of pancreatic islet-like cells from isolated monocyte-derived stem cells (MDSCs) is provided. MDSCs may be differentiated into pancreatic islet cells by contacting the MDSCs with a differentiation factor or factors. Compositions comprising pancreatic islet cells and methods of using them are also provided.

La présente invention concerne la production de cellules du type îlots pancréatiques produites à partir de cellules souches dérivées de monocytes (MDSC). Ces MDSC peuvent être différenciées en cellules des îlots pancréatiques par mise en contact desdites MDSC avec un ou plusieurs facteurs de différentiation. Des compositions contenant des cellules des îlots pancréatiques et des méthodes d'utilisation desdites cellules sont également décrites.

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